Reactive oxygen species and sperm DNA fragmentation
نویسندگان
چکیده
منابع مشابه
Reactive oxygen species and sperm DNA fragmentation
tau.amegroups.com © Translational Andrology and Urology. All rights reserved. Dr. Dada demonstrated her extensive knowledge about sperm DNA fragmentation (SDF) in her elegantly written commentary with a comprehensive discussion on issues such as genetic health of offspring, value of SDF testing in lifestyle factors, modification of SDF by oocyte, role of sperm preparation, concept of reductive ...
متن کاملMalonaldehyde formation and DNA fragmentation: two independent sperm decays linked to reactive oxygen species.
Malondialdehyde (MDA), a product involved in membrane lipid peroxidation, was dosed in the sperm of 163 patients who had consulted the clinic regarding hypofertility. We attempted to determine if there was correlation between MDA content, sperm World Health Organization parameters and DNA fragmentation that results mainly from reactive oxygen species assaults. We found that no correlation could...
متن کاملO-15: Different Leukocyte Concentrations in Normal and Abnormal Human Semen and Its Correlation with Sperm Intracellular Reactive Oxygen Species, Lipid Peroxidation and DNA Fragmentation
Background: According to World Health Organization guideline (WHO 2010), seminal leukocyte concentration over 1×106/mL is a threat for sperm quality because of their role in reactive oxygen species (ROS) production, lipid per-oxidation (LPO) and later DNA fragmentation (DF). However, this threshold is equal for all semen samples without attention to their qualities. Therefore this study was set...
متن کاملReactive oxygen species and sperm physiology.
Although high concentrations of reactive oxygen species (ROS) cause sperm pathology (ATP depletion leading to insufficient axonemal phosphorylation, lipid peroxidation and loss of motility and viability), recent evidence demonstrates that low and controlled concentrations of these ROS play an important role in sperm physiology. Reactive oxygen species, such as the superoxide anion, hydrogen per...
متن کاملReactive oxygen species and sperm cells
There is a dynamic interplay between pro- and anti-oxidant substances in human ejaculate. Excessive reactive oxygen species (ROS) generation can overwhelm protective mechanism and initiate changes in lipid and/or protein layers of sperm plasma membranes. Additionally, changes in DNA can be induced. The essential steps of lipid peroxidation have been listed as well as antioxidant substances of s...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
ژورنال
عنوان ژورنال: Translational Andrology and Urology
سال: 2017
ISSN: 2223-4683,2223-4691
DOI: 10.21037/tau.2017.05.40